Rexahn completes enrollment for phase 2 antidepressant drug trial

Rexahn’s goal is to be a world-class biopharmaceutical company developing and delivering novel cures for cancer and disorders of the central nervous system (CNS) to patients worldwide. Leveraging a powerful, multi-faceted discovery engine consisting of small signaling molecule discovery, computational modeling and nanotechnology-based drug targeting and delivery, we believe that we are well on our way to achieving our goal.

Rexahn Pharmaceuticals ( AMEX:RNN ) said Wednesday it has completed enrollment for its phase two clinical trial of Serdaxin, a potential antidepressant.

The randomized, double-blind, placebo-controlled study, which will assess the efficacy of the drug based on a depression rating scale, began enrollment in January, enlisting a total of 300 patients at around 40 sites in the US.

The company said it expects to report preliminary findings from the trial later this year.

"We are very excited by the speed at which we've completed enrollment in our Phase IIb trial for Serdaxin and believe that this further validates the current unmet need for an effective treatment for major depressive disorder," said president and COO Rick Soni.

Serdaxin works to enhance both serotonin and dopamine, two neurotransmitters, and is therefore a potential treatment for multiple central nervous system disorders where these neurotransmitters are depleted, such as Parkinson's disease.

Rexahn has multiple clinical programs planned for investigating Serdaxin in the treatment of anxiety disorders, Parkinson's disease, Alzheimer's disease and neurodegenerative illnesses.

The company currently has two other drug candidates in phase two clinical trials, including Archexin, and Zoraxel. No investment advice

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Anxiety Disorders Children References - News


Rexahn completes enrollment for phase 2 antidepressant drug trial

Rexahn has multiple clinical programs planned for investigating Serdaxin in the treatment of anxiety disorders, Parkinson's disease, Alzheimer's disease and neurodegenerative illnesses. The company currently has two other drug candidates in phase two



News events can prompt post-traumatic stress disorder in children

Post-traumatic stress disorder describes the same set of symptoms but may occur a month or so later. In many cases, children may relive the disaster, becoming jumpy and startled, or they may avoid any reference to the experience.



Lewis: What really lurks in the mind of Barry Minkow

The document references an evaluation by a Dr. Michael Brannon on May 10. "Included in Dr. Brannon's evaluation of Mr. Minkow is a diagnosis that includes Attention-Deficit/Hyperactivity Disorder, Anxiety Disorder Opioid Dependence Disorder



Do I wait for boyfriend to choose between lives?

The Anxiety Disorders Association of Manitoba (ADAM, 925-0600) offers a course for handling anxiety that is excellent for some people. Their website www.adam.mb.ca offers resources for different types of anxiety. Questions or comments?



The Problem With... Taylor Swift's "The Story of Us"

I've always said that, below the surface, Swift's tunes are like pop-country interpretations of the health reference book, DSM-IV. I'm sure she wrote the entry on boy-craziness. This time, "The Story of Us" details social anxiety disorder.




Stress and Anxiety Disorders in Children – Part 2 | Anxiety ...

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Anxiety Disorders Children References - Bookshelf

Handbook of Anxiety Disorders in Children and Adolescents

Handbook of Anxiety Disorders in Children and Adolescents

References Amaral, DG (2003). The amygdala, social behavior, ... Emotion regulation and anxiety disorders. Journal of Anxiety Disorders, 22, 211–221. ...

The Mental Health Desk Reference, A Practice-Based Guide to Diagnosis, Treatment, and Professional Ethics

The Mental Health Desk Reference, A Practice-Based Guide to Diagnosis, Treatment, and Professional Ethics

For an excellent review of depression scales and checklists in children, see Compas (1997). Anxiety Disorders Childhood fears and anxieties are so common ...

Residential and inpatient treatment of children and adolescents

Residential and inpatient treatment of children and adolescents

Anxiety Disorders No well-controlled study has proven the efficacy of psychotropic medication on anxiety disorders of children and adolescents, ...

Anxiety disorders in children and adolescents

Anxiety disorders in children and adolescents

REFERENCES Agras, WS, Chapin, NH, & Oliveau, DC (1972). ... In JS March (Ed.), Anxiety disorders in children and adolescents (pp. 109-124). ...

Social Behavior and Skills in Children

Social Behavior and Skills in Children

Anxiety in a neglected population: Prevalence of anxiety disorders in pre- adolescent children. Clinical Psychology Review, 26, 817–833. ...

Daily Guide Directory


Mental Health: A Report of the Surgeon General - Chapter 3
Other Mental Disorders in Children and Adolescents. Anxiety Disorders ... Children with generalized anxiety disorder (or overanxious disorder of childhood) ...

Anxiety In Children - Research and Read Books, Journals ...
Anxiety In Children - Scholarly books, journals and articles Anxiety In Children at Questia, world's largest online library and research service. ...

Separation anxiety disorder - Wikipedia, the free encyclopedia
Separation Anxiety Disorder (SAD), is characterized by significant ... Studies show that children suffering from separation anxiety disorder are much more ...

Anxiety Disorders in Children
Anxiety disorders in children include phobias, generalized anxiety, ... c. Separation anxiety disorder may not manifest until 8-10 years of age after a holiday ...

Generalized Anxiety Disorder-References
CitationsSadock BJ, Sadock VA, eds. (2003). Generalized anxiety disorder section of Anxiety disorders. In Kaplan and Sadock's Synopsis of Psychiatry: Behavioral ...